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May 31
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A MyFoodAllergyTeam Member

So if my milk allergy is being caused by alpha gal it would not benefit from solar but my peanuts would? Can this be a preventive for further OAS type allergies?

May 31
MyFoodAllergyTeam

Great question! Xolair (omalizumab) works by targeting and blocking IgE antibodies, which are the proteins responsible for triggering allergic reactions. It was FDA-approved in February 2024 to help reduce the risk of severe allergic reactions from food allergens.

However, it's important to understand a key distinction Show Full Answer

Great question! Xolair (omalizumab) works by targeting and blocking IgE antibodies, which are the proteins responsible for triggering allergic reactions. It was FDA-approved in February 2024 to help reduce the risk of severe allergic reactions from food allergens.

However, it's important to understand a key distinction here:

- IgE-mediated allergies (like peanut, milk, eggs, tree nuts, wheat, and shellfish) are directly targeted by Xolair because these reactions are driven by IgE antibodies
- Oral allergy syndrome (OAS) is a subtype of IgE-mediated food allergies, so Xolair could potentially be relevant, but it's best to discuss this specifically with an allergist
- Alpha-gal syndrome works differently — it's triggered by a carbohydrate molecule rather than a typical IgE-driven protein response, making it less clear whether Xolair would be effective for it It's worth noting that Xolair is not meant to treat anaphylaxis once it occurs — it's a preventive treatment. Always carry epinephrine as a backup.

Speaking with an allergist is the best way to find out if Xolair is right for a specific allergy situation.

May 31

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