Overview
EpiPen is approved by the U.S. Food and Drug Administration (FDA) for the emergency treatment of severe allergic reactions (type I), including anaphylaxis. It is intended for individuals who are at risk for or have a history of anaphylaxis due to triggers including food. EpiPen should be used immediately at the first signs of a serious allergic reaction and followed by immediate medical attention. EpiPen is also known by its drug name, epinephrine.

EpiPen is an adrenergic agonist. It works by narrowing blood vessels and opening airways in the lungs, which can reverse severe low blood pressure, wheezing, skin itching, hives, and other symptoms of anaphylaxis.

How do I take it?
Prescribing information states that EpiPen is administered as a single-dose intramuscular (into a muscle) or subcutaneous (under the skin) injection into the outer thigh. It can be injected through clothing if necessary. EpiPen is intended for individuals who weigh 30 kilograms (66 pounds) or more. EpiPen should be taken exactly as prescribed by a healthcare provider.

Side effects
Common side effects of EpiPen include anxiety, apprehensiveness, restlessness, tremor, weakness, dizziness, sweating, palpitations (irregular or fast heartbeat), pallor (pale skin), nausea and vomiting, headache, and/or respiratory difficulties.

Rare but serious side effects may include serious skin and soft tissue infections, ventricular arrhythmias (irregular heartbeats in the lower chambers), and worsening of existing heart conditions such as angina pectoris (chest pain). Elderly individuals may be at greater risk of experiencing adverse effects.

For more information about this treatment, visit:

Label: EpiPen — Epinephrine Injection — DailyMed